Last edited by Doukasa
Wednesday, May 13, 2020 | History

8 edition of RNA and the Regulation of Gene Expression found in the catalog.

RNA and the Regulation of Gene Expression

A Hidden Layer of Complexity

by Kevin V. Morris

  • 256 Want to read
  • 24 Currently reading

Published by Caister Academic Pr .
Written in English

    Subjects:
  • Genetics (non-medical),
  • Life Sciences - Biology - Molecular Biology,
  • Life Sciences - Genetics & Genomics,
  • Science,
  • Science/Mathematics

  • The Physical Object
    FormatHardcover
    Number of Pages300
    ID Numbers
    Open LibraryOL12290841M
    ISBN 101904455255
    ISBN 109781904455257

    coding RNA concerning there expression the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed. Post-transcriptional regulation is the control of gene expression at the RNA level, therefore between the transcription and the translation of the gene. It contributes substantially to gene expression regulation across human tissues. Mechanism. This section needs additional citations for verification. Please help improve this article by.

    Alternative RNA Splicing. In the s, genes were first observed that exhibited alternative RNA splicing. Alternative RNA splicing is a mechanism that allows different protein products to be produced from one gene when different combinations of exons are combined to form the mRNA (Figure ).This alternative splicing can be haphazard, but more often it is controlled and acts as a mechanism.   This is a key point of regulation of eukaryotic gene expression. Here, several factors such as promoters and enhancers alter the ability of RNA polymerase to .

    In eukaryotes, regulation of gene expression doesn’t involve repressor or activator proteins. Instead, signals to turn on and off transcription are sent directly to parts of the RNA polymerase enzyme itself. Cancer can be described as a disease of altered gene expression. Changes at every level of eukaryotic gene expression can be detected in some form of cancer at some point in time. In order to understand how changes to gene expression can cause cancer, it is critical to understand how each stage of gene regulation works in normal cells.


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RNA and the Regulation of Gene Expression by Kevin V. Morris Download PDF EPUB FB2

In this book, internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, as well as highlight the application of this knowledge in therapeutics and : Hardcover.

This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by Cited by: The role of RNA in regulating gene expression has become a topic of intense interest.

In this book internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research.5/5(1).

In this book internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research.

The role of RNA in regulating gene expression has become a topic of intense interest. In this book internationally recognized experts explore and discuss the methods whereby RNA and the Regulation of Gene Expression book can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research.

Book Review: RNA and the Regulation of Gene Expression. By K. Morris (Ed.) Article in Engineering in Life Sciences 8(3) June with 4 Reads. Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation.

The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms. As explained in the previous sections, conversion of a 5′ capped RNA transcript into a functional mRNA involves two primary steps: (1) cleavage and polyadenylation at the 3′ end and (2) ligation of exons with the concomitant excision of introns, or RNA splicing.

To understand how regulation of RNA processing can control gene expression, we need to recall that higher eukaryotes contain both Author: Harvey Lodish, Arnold Berk, S Lawrence Zipursky, Paul Matsudaira, David Baltimore, James Darnell. Eukaryotic gene expression is regulated during transcription and RNA processing, which take place in the nucleus, and during protein translation, which takes place in the cytoplasm.

Further regulation may occur through post-translational modifications of proteins. Transcription- In this step, with the help of RNA polymerase enzymes, the messenger RNA is produced resulting in the processing of mRNA molecule. Translation- The main function of mRNA is to direct the synthesis of a protein resulting in the succeeding post-translational processing of the protein molecules.

Regulation of Gene Expression. The symposium related gene structure and regulatory sequences to overall genomic organization and genetic evolution. It was the first meeting to focus on regulation of eukaryotic gene expression since the maturation in recombinant DNA technology.

The book is organized into four parts. actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and. A wide variety of noncoding RNA molecules, both long and short, are involved in regulating gene expression.

There are major differences between prokaryotes and eukaryotes. Prokaryotes use relatively few regulatory RNAs and these are usually short. Book: General Biology (OpenStax) Unit III: Genetics Gene Expression Because proteins are involved in every stage of gene regulation, the phosphorylation of a protein (depending on the protein that is modified) can alter accessibility to the chromosome, can alter translation (by altering transcription factor binding or function), can.

RNA Processing and Turnover Although transcription is the first and most highly regulated step in gene expression, it is usually only the beginning of the series of events required to produce a functional RNA. Most newly synthesized RNAs must be modified Author: Geoffrey M Cooper. RNA and the regulation of gene expression: a hidden layer of complexity.

[Kevin V Morris;] -- "In this book internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals and viral.

Faculty who are investigating the regulation of gene expression are interested in numerous topics including transcriptional regulatory pathways in pro- and eukaryotes, DNA and RNA interactions with proteins, RNA processing and the functions of catalytic RNA, chromatin modification and remodeling, and three-dimensional organization of genes in.

of the current high throughput technologies used in measuring gene expression, followed by a summary of computational methods for quantifying gene expression based on the determination of the sequence of RNA molecules (RNA-seq).

The regulation of gene expression The abundance of di erent RNAs (also called transcripts) in a cell at any given.

MicroRNAs represent the most important gene regulatory small RNAs and act by tuning the expression level of eukaryotic mRNAs. Interestingly, endogenous siRNAs as well as piRNAs apparently serve both regulatory and defensive purposes.

They suppress the expression of repetitive DNA elements but also influence the expression of protein coding genes. Any step of gene expression may be modulated, from the DNA-RNA transcription step to post-translational modification of a protein. The stability of the final gene product, whether it is RNA or protein, also contributes to the expression level of the gene—an.

RNA & Gene Regulation Genome Biology 's special issue will shed new light on this important area. Alternative polyadenylation factors link cell cycle to migration In response to a wound, fibroblasts are activated to migrate toward the wound, to proliferate and .Learn for free about math, art, computer programming, economics, physics, chemistry, biology, medicine, finance, history, and more.

Khan Academy is a nonprofit with the mission of providing a free, world-class education for anyone, anywhere.A: Overview of Gene Expression. B: Overview of Transcription. RNA Polymerases; C: Gene's Regulatory Elements. Promoter; The lac Operon Promoter; The IL-2 Promoter; Enhancer; Silencer; Response Elements; D: Transcription Mechanisms in Prokaryotes.

Transcriptional Termination in Prokaryotes; Regulation of lac Operon Transcription; Activation of.